O.J. Simpson appears in the Season Five episode, 'Butters' Very Own Episode', in which he joined Butters' parents in searching for 'some Puerto Rican guy', who is allegedly responsible for Butters' disappearance and Nicole Brown Simpson's death. He appears in '200' at Tom Cruise's house, despite being in prison for an unrelated crime when '200' aired. O.J. is also referenced many times in the episode 'Chef Aid'. He also appeared in a The Simpsons sketch parodying South Park. (Source: Fandom.com, CC BY-SA)